PPP2R1A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1497

Novus Biologicals, part of Bio-Techne
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NB100-1497
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all PPP2R1A Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KYFAQEALTVLSLA corresponding to C-Terminus according to NP_055040.2.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for PPP2R1A Antibody

Western Blot: PPP2R1A Antibody [NB100-1497]

Western Blot: PPP2R1A Antibody [NB100-1497]

Western Blot: PPP2R1A Antibody [NB100-1497] - Staining of Human Thymus (A) and Human Lymph node (B) lysates (35 ug protein in RIPA buffer). Antibody at 2 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for PPP2R1A Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:14000

Western Blot

2 - 6 ug/mL

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PPP2R1A

Protein phosphatase 2A (PP2A) is the most abundant phosphatase specific for serine and threonine phosphorylation in mammalian cells. Dephosphorylation of substrates targeted by PP2A plays a vital role in a large variety of cellular processes including signal transduction, regulation of the cell cycle, gene expression and development. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit alpha serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory beta subunit.

Alternate Names

Medium tumor antigen-associated 61 kDa protein, MGC786, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha, PP2AAALPHA, PP2A-Aalpha, PR65A, protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alphaisoform, protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform, protein phosphatase 2, regulatory subunit A, alpha, serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alphaisoform, serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alphaisoform

Entrez Gene IDs

5515 (Human)

Gene Symbol

PPP2CA

UniProt

NP_055040. (Human)

Additional PPP2R1A Products

Product Documents for PPP2R1A Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PPP2R1A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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