PPP3CC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19911

Novus Biologicals, part of Bio-Techne
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NBP2-19911
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (97%), Mouse (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PPP3CC Antibodies »

Product Summary for PPP3CC Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human PPP3CC. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rabbit (84%),Xenopus tropicalis (86%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PPP3CC Antibody

Western Blot: PPP3CC Antibody [NBP2-19911]

Western Blot: PPP3CC Antibody [NBP2-19911]

Western Blot: PPP3CC Antibody [NBP2-19911] - Sample (30 ug of whole cell lysate) A: NT2D1 B: IMR32 7. 5% SDS PAGE gel, diluted at 1:5000.

Applications for PPP3CC Antibody

Application
Recommended Usage

Western Blot

1:1000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PPP3CC

Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).[supplied by OMIM]

Long Name

Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

Alternate Names

CALNA3, CNA3

Gene Symbol

PPP3CC

UniProt

P48454 (Human)

Additional PPP3CC Products

Product Documents for PPP3CC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PPP3CC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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