PPP3R2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00005535-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PPP3R2 Antibodies »

Product Specifications

Immunogen

PPP3R2 (NP_671709.1, 1 a.a. - 173 a.a.) full-length human protein. MSTMGNEASYPAEMCSHFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRRVIDVFDTDGDGEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLKMMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEFSAVVRDLEIHKKLVLIV

Specificity

Reacts with protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for PPP3R2 Antibody

Western Blot: PPP3R2 Antibody [H00005535-D01P]

Western Blot: PPP3R2 Antibody [H00005535-D01P]

Western Blot: PPP3R2 Antibody [H00005535-D01P] - Analysis of PPP3R2 expression in transfected 293T cell line by PPP3R2 polyclonal antibody.Lane 1: PPP3R2 transfected lysate(19.90 KDa).Lane 2: Non-transfected lysate.

Applications for PPP3R2 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PPP3R2

PPP3R2 also known as Calcineurin subunit B type 2, is a 170 amino acid protein that is 20 kDa, is testis-specific, is a regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase, and confers calcium sensitivity. This protein is being studied for its involvement in amyotrophic lateral sclerosis (als), amyotrophic lateral sclerosis, lateral sclerosis, tuberculosis, malaria, and neuronitis. PPP3R2 protein is involved is several pathways including MAPK signaling pathway, Alzheimer's Disease, Energy Metabolism, Calcium signaling pathway, Oocyte meiosis, Apoptosis, Wnt signaling pathway, Tacrolimus/Cyclosporine Pathway, Pharmacodynamics, 14-3-3 Induced Apoptosis, Intracellular Calcium Signaling, PI3K Signaling in B-Lymphocyte, IL-2 Pathway, and ITK and TCR Signaling Pathway where it interacts with TBC1D10C, PLCG1, PLCG2, ANAPC1, ANAPC10, and approx. 30 other proteins.

Long Name

Calcineurin subunit B type 2

Alternate Names

Calcineurin BII, CBLP, CNBII, PPP3R1-like, PPP3RL

Entrez Gene IDs

5535 (Human)

Gene Symbol

PPP3R2

UniProt

NP_671709.1 (Human)

Additional PPP3R2 Products

Product Documents for PPP3R2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PPP3R2 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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