PPP4R2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58011

Novus Biologicals, part of Bio-Techne
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NBP2-58011
NBP2-58011-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PPP4R2 Antibodies »

Product Summary for PPP4R2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: KESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPM

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PPP4R2 Antibody

Immunocytochemistry/ Immunofluorescence: PPP4R2 Antibody [NBP2-58011]

Immunocytochemistry/ Immunofluorescence: PPP4R2 Antibody [NBP2-58011]

Immunocytochemistry/Immunofluorescence: PPP4R2 Antibody [NBP2-58011] - Staining of human cell line U-2 OS shows localization to nucleoplasm.

Applications for PPP4R2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PPP4R2

Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C atcentrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporallocalization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replicationand required for DNA DSB repair

Alternate Names

MGC131930, PP4R2, protein phosphatase 4, regulatory subunit 2, serine/threonine-protein phosphatase 4 regulatory subunit 2

Gene Symbol

PPP4R2

Additional PPP4R2 Products

Product Documents for PPP4R2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PPP4R2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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