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PRAM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31075

Novus Biologicals, part of Bio-Techne
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NBP1-31075

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PRAM1. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

79 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PRAM1 Antibody

Western Blot: PRAM1 Antibody [NBP1-31075]

Western Blot: PRAM1 Antibody [NBP1-31075]

Western Blot: PRAM1 Antibody [NBP1-31075] - Sample(30 ug of whole cell lysate)A:293T7. 5% SDS PAGE, antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: PRAM1 Antibody [NBP1-31075]

Immunohistochemistry-Paraffin: PRAM1 Antibody [NBP1-31075]

Immunohistochemistry-Paraffin: PRAM1 Antibody [NBP1-31075] - Paraffin-embedded Colon Carcinoma; antibody dilution 1:500.

Applications for PRAM1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PRAM1

The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).

Alternate Names

MGC39864, PML-RAR, PML-RARA regulated adaptor molecule 1, PML-RARA target gene encoding an Adaptor Molecule-1, PML-RARA-regulated adapter molecule 1, PRAM, PRAM-1

Gene Symbol

PRAM1

Additional PRAM1 Products

Product Documents for PRAM1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PRAM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.