Pregnancy Zone Protein Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85489

Novus Biologicals, part of Bio-Techne
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NBP1-85489
NBP1-85489-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Pregnancy Zone Protein/PZP Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHNGAIYVPLSSNEADIYSFLKGMGL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Pregnancy Zone Protein Antibody

Immunohistochemistry-Paraffin: Pregnancy Zone Protein Antibody [NBP1-85489]

Immunohistochemistry-Paraffin: Pregnancy Zone Protein Antibody [NBP1-85489]

Immunohistochemistry-Paraffin: Pregnancy Zone Protein Antibody [NBP1-85489] - Staining of human kidney shows distinct cytoplasmic and extracellular positivity in renal tubules.

Applications for Pregnancy Zone Protein Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Pregnancy Zone Protein/PZP

PZP is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Alternate Names

CPAMD6, PZP

Gene Symbol

PZP

Additional Pregnancy Zone Protein/PZP Products

Product Documents for Pregnancy Zone Protein Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Pregnancy Zone Protein Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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