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Presenilin-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33611

Novus Biologicals, part of Bio-Techne
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NBP1-33611

Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Presenilin-1. The exact sequence is proprietary.

Localization

Endoplasmic reticulum membrane, Multi-pass membrane protein, Golgi apparatus membrane, Multi-pass membrane protein, Cell surface

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Presenilin-1 Antibody

Western Blot: Presenilin-1 Antibody [NBP1-33611]

Western Blot: Presenilin-1 Antibody [NBP1-33611]

Western Blot: Presenilin-1 Antibody [NBP1-33611] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611]

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611]

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded mouse brain. Presenilin 1 antibody [C1C2], Internal dilution: 1:500.
Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611]

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611]

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded Cal27 xenograft, using antibody at 1:100 dilution.

Applications for Presenilin-1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Presenilin-1

PSDR1 is a novel prostate short-chain dehydrogenase/reductase that exhibits increased expression on exposure to androgens in the LNCaP prostate cancer cell line. PSDR1 is expressed in normal and neoplastic prostate epithelium and is implicated in the pathogenesis of prostate carcinoma.

Alternate Names

Presenilin1, PSEN1, S182

Gene Symbol

PSEN1

Additional Presenilin-1 Products

Product Documents for Presenilin-1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Presenilin-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.