PRKCDBP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57897

Novus Biologicals, part of Bio-Techne
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NBP2-57897
NBP2-57897-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PRKCDBP Antibodies »

Product Summary for PRKCDBP Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EAQPEAQPALEPTLEPEPPQDTEEDPGRPGAAEEALLQMESVA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PRKCDBP Antibody

Immunocytochemistry/ Immunofluorescence: PRKCDBP Antibody [NBP2-57897]

Immunocytochemistry/ Immunofluorescence: PRKCDBP Antibody [NBP2-57897]

Immunocytochemistry/Immunofluorescence: PRKCDBP Antibody [NBP2-57897] - Staining of human cell line A-431 shows localization to plasma membrane.

Applications for PRKCDBP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRKCDBP

PRKCDBP, also known as Protein kinase C delta-binding protein, is 261 amino acids in length and approximately 27kDa. PRKCDBP is highly expressed in epithelial cells, and is down regulated in lung cancer cell lines and breast cancer cell lines, thus suggesting the possibility of tumor suppressor function. PRKCDBP binds and is phosphorylated by protein kinase C, delta. Current research surrounding PRKCDBP shows a possible connection with ovarian cancer, gastric cancer and lung cancer. PRKCDBP has also been shown to interact with Caveolin 1, Caveolin 3, cMyc, SDPR, and EPS15L1.

Alternate Names

cavin-3, HSRBC, MGC20400, protein kinase C, delta binding protein, sdr-related gene product that binds to c-kinase, Serum deprivation response factor-related gene product that binds to C-kinase, SRBCprotein kinase C delta-binding protein

Gene Symbol

CAVIN3

Additional PRKCDBP Products

Product Documents for PRKCDBP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PRKCDBP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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