PRMT6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56642

Novus Biologicals, part of Bio-Techne
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NB100-56642
NB100-56642SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

In vitro assay, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all PRMT6 Antibodies »

Product Specifications

Immunogen

This antibody was developed a synthetic peptide corresponding to amino acids 23-43 (CEEDGAEREAALERPRRTKRER) of human PRMT6.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PRMT6 Antibody

Western Blot: PRMT6 Antibody [NB100-56642]

Western Blot: PRMT6 Antibody [NB100-56642]

Western Blot: PRMT6 Antibody [NB100-56642] - Mouse 4T1 cells and EMT6 cells whole cell lysate. Image from verified customer review.
Western Blot: PRMT6 Antibody [NB100-56642]

Western Blot: PRMT6 Antibody [NB100-56642]

Western Blot: PRMT6 Antibody [NB100-56642] - Analysis of PRMT6 in HeLa lysate using PRMT6 antibody at 1:500 dilution.

Applications for PRMT6 Antibody

Application
Recommended Usage

In vitro assay

reported in scientific literature (PMID 29973649)

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 3 reviews rated 4.7 using NB100-56642 in the following applications:

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole antisera with PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRMT6

Protein arginine methylation is an important posttranslational modification in eukaryotic cells, which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. PRMT6 was identified by searching the human genome for protein arginine N-methyltransferase (PRMT) family members. PRMT6 cDNA codes for a protein of approximate molecular weight of 42 kDa consisting of a catalytic core sequence common to other PRMT enzymes. PRMT6 demonstrates type I PRMT activity, capable of forming both >NG-monomethylarginine and asymmetric >NG,NG-dimethylarginine derivatives on the recombinant glycine- and arginine-rich substrates. A comparison of substrate specificity reveals that PRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition to methylating substrate proteins, PRMT6 displays automethylation activit. GFP-fusion protein expression in the transfected cell lines suggest that PRMT6 localizes in the nucleus.

Long Name

Protein arginine N-methyltransferase 6

Alternate Names

HRMT1L6

Entrez Gene IDs

55170 (Human); 99890 (Mouse)

Gene Symbol

PRMT6

UniProt

Q96LA8 (Human)

Additional PRMT6 Products

Product Documents for PRMT6 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PRMT6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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