Proprotein Convertase 1/PCSK1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13741

Novus Biologicals, part of Bio-Techne
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NBP2-13741
NBP2-13741-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Proprotein Convertase 1/PCSK1 Antibodies »

Product Summary for Proprotein Convertase 1/PCSK1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: RQFVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Proprotein Convertase 1/PCSK1 Antibody

Immunohistochemistry-Paraffin: Proprotein Convertase 1/PCSK1 Antibody [NBP2-13741]

Immunohistochemistry-Paraffin: Proprotein Convertase 1/PCSK1 Antibody [NBP2-13741]

Immunohistochemistry-Paraffin: PC1/3 Antibody [NBP2-13741] Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Applications for Proprotein Convertase 1/PCSK1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Proprotein Convertase 1/PCSK1

This family of serine proteases consists of furin and proprotein convertases encoded by PCSK genes. They are important in a variety of processes. Furin has an essential role in embryogenesis and homeostasis and is implicated in various pathologies such as cancer, neurodegenerative diseases and anthrax. Mutations in the PC1/PCSK1 gene are associated with obesity and impaired prohormone processing.

Alternate Names

NEC1, PCSK1

Gene Symbol

PCSK1

Additional Proprotein Convertase 1/PCSK1 Products

Product Documents for Proprotein Convertase 1/PCSK1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Proprotein Convertase 1/PCSK1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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