Prostaglandin E Synthase Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87852

Novus Biologicals, part of Bio-Techne
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NBP1-87852
NBP1-87852-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Predicted:

Rat (91%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Prostaglandin E Synthase Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAPRNDM

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 27102561).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Prostaglandin E Synthase Antibody

Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852]

Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852]

Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Analysis in human seminal vesicle and pancreas tissues. Corresponding Prostaglandin E Synthase RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: Prostaglandin E Synthase Antibody [NBP1-87852]

Immunocytochemistry/ Immunofluorescence: Prostaglandin E Synthase Antibody [NBP1-87852]

Immunocytochemistry/Immunofluorescence: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human cell line SiHa shows localization to endoplasmic reticulum. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852]

Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852]

Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human urinary bladder shows moderate cytoplasmic positivity in urothelial cells.
View 4 more images

Applications for Prostaglandin E Synthase Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Prostaglandin E Synthase

Prostaglandin E Synthase is encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq]

Long Name

Prostaglandin E synthase

Alternate Names

EC 5.3.99.3, MGST1-L1, MGST1L1, MPGES-1, MPGES1, PGES, PIG12, PTGES

Gene Symbol

PTGES

Additional Prostaglandin E Synthase Products

Product Documents for Prostaglandin E Synthase Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Prostaglandin E Synthase Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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