Proteasome beta 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89714

Novus Biologicals, part of Bio-Techne
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NBP1-89714
NBP1-89714-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Proteasome beta 1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Proteasome beta 1 Antibody

Immunohistochemistry-Paraffin: Proteasome beta 1 Antibody [NBP1-89714]

Immunohistochemistry-Paraffin: Proteasome beta 1 Antibody [NBP1-89714]

Immunohistochemistry-Paraffin: Proteasome beta 1 Antibody [NBP1-89714] - Staining of human colon, kidney, liver and testis using Anti-PSMB1 antibody NBP1-89714 (A) shows similar protein distribution across tissues to independent antibody NBP1-89713 (B).
Western Blot: Proteasome beta 1 Antibody [NBP1-89714]

Western Blot: Proteasome beta 1 Antibody [NBP1-89714]

Western Blot: Proteasome beta 1 Antibody [NBP1-89714] - Analysis using Anti-PSMB1 antibody NBP1-89714 (A) shows similar pattern to independent antibody NBP1-89713 (B).
Immunocytochemistry/ Immunofluorescence: Proteasome beta 1 Antibody [NBP1-89714]

Immunocytochemistry/ Immunofluorescence: Proteasome beta 1 Antibody [NBP1-89714]

Immunocytochemistry/Immunofluorescence: Proteasome beta 1 Antibody [NBP1-89714] - Staining of human cell line Hep G2 shows localization to nucleus. Antibody staining is shown in green.
View 4 more images

Applications for Proteasome beta 1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Proteasome beta 1

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq]

Long Name

Proteasome subunit beta type-1

Alternate Names

PSC5, PSMB1

Gene Symbol

PSMB1

Additional Proteasome beta 1 Products

Product Documents for Proteasome beta 1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Proteasome beta 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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