Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Mouse (100%), Rat (100%), Xenopus (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all Protein Phosphatase 1C gamma Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 280 and the C-terminus (residue 323) of human Protein Phosphatase 1, Catalytic Subunit, Gamma Isoform using the numbering given in entry NP_002701.1 (GeneID 5501).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Protein Phosphatase 1C gamma Antibody

Western Blot: Protein Phosphatase 1C gamma Antibody [NB110-40551]

Western Blot: Protein Phosphatase 1C gamma Antibody [NB110-40551]

Western Blot: Protein Phosphatase 1C gamma Antibody [NB110-40551] - Whole cell lysate (50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. NB110-40551 used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate (B). PPP1CB was also immunoprecipitated by NB110-40551.
Immunohistochemistry-Paraffin: Protein Phosphatase 1C gamma Antibody [NB110-40551]

Immunohistochemistry-Paraffin: Protein Phosphatase 1C gamma Antibody [NB110-40551]

Immunohistochemistry-Paraffin: Protein Phosphatase 1C gamma Antibody [NB110-40551] - Human breast carcinoma. Antibody: Affinity purified rabbit anti- PPP1CC used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

Applications for Protein Phosphatase 1C gamma Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:2000

Immunohistochemistry-Paraffin

1:250

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
Epitope retrieval with Tris-EDTA pH9.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Protein Phosphatase 1C gamma

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternate Names

EC 3.1.3.16, PP-1G, PP1gamma, PPP1G, protein phosphatase 1, catalytic subunit, gamma isoform, protein phosphatase 1, catalytic subunit, gamma isozyme, Protein phosphatase 1C catalytic subunit, serine/threonine phosphatase 1 gamma, serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Entrez Gene IDs

5501 (Human)

Gene Symbol

PPP1CC

UniProt

P36873 (Human)

Additional Protein Phosphatase 1C gamma Products

Product Documents for Protein Phosphatase 1C gamma Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Protein Phosphatase 1C gamma Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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