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Proteinase 3/Myeloblastin/PRTN3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00005657-D01P

Novus Biologicals, part of Bio-Techne
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H00005657-D01P

Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

PRTN3 (AAH96184.1, 1 a.a. - 256 a.a.) full-length human protein. MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP

Specificity

PRTN3 - proteinase 3 (serine proteinase, neutrophil, Wegener granulomatosis autoantigen),

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Proteinase 3/Myeloblastin/PRTN3 Antibody

Western Blot: Proteinase 3/Myeloblastin/PRTN3 Antibody [H00005657-D01P]

Western Blot: Proteinase 3/Myeloblastin/PRTN3 Antibody [H00005657-D01P]

Western Blot: Proteinase 3/Myeloblastin/PRTN3 Antibody [H00005657-D01P] - Analysis of PRTN3 expression in mouse brain.
Western Blot: Proteinase 3/Myeloblastin/PRTN3 Antibody [H00005657-D01P]

Western Blot: Proteinase 3/Myeloblastin/PRTN3 Antibody [H00005657-D01P]

Western Blot: Proteinase 3/Myeloblastin/PRTN3 Antibody [H00005657-D01P] - Analysis of PRTN3 expression in transfected 293T cell line by PRTN3 polyclonal antibody.Lane 1: PRTN3 transfected lysate(27.80 KDa).Lane 2: Non-transfected lysate.

Applications for Proteinase 3/Myeloblastin/PRTN3 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Proteinase 3/Myeloblastin/PRTN3

Myeloblastin (PR3) is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. PR3 plays a role in neutrophil response to inflammation.

Alternate Names

ACPA, AGP7, C-ANCA, MBN, MBT, Myeloblastin, NP4, PRTN3

Entrez Gene IDs

5657 (Human)

Gene Symbol

PRTN3

Additional Proteinase 3/Myeloblastin/PRTN3 Products

Product Documents for Proteinase 3/Myeloblastin/PRTN3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Proteinase 3/Myeloblastin/PRTN3 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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