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PRRX1 Antibody (CL14471)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26856

Novus Biologicals, part of Bio-Techne
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NBP3-26856-100ul
NBP3-26856-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Clone # CL14471

Concentration

1 mg/ml

Product Summary for PRRX1 Antibody (CL14471)

Immunogen

This antibody was developed against a Synthetic Peptide of P54821. Actual immunogen sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3

Scientific Data Images for PRRX1 Antibody (CL14471)

PRRX1 Antibody (CL14471)

Immunohistochemistry-Paraffin: PRRX1 Antibody (CL14471) [NBP3-26856]

Staining of human liver shows no nuclear positivity in hepatocytes as expected.
PRRX1 Antibody (CL14471)

Immunohistochemistry-Paraffin: PRRX1 Antibody (CL14471) [NBP3-26856]

Staining of human endometrium shows strong nuclear positivity in glandular cells.
PRRX1 Antibody (CL14471)

Immunohistochemistry-Paraffin: PRRX1 Antibody (CL14471) [NBP3-26856]

Staining of human uterine cervix shows strong nuclear positivity in squamous epithelial cells.

Applications for PRRX1 Antibody (CL14471)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Immunohistochemistry

1:50 - 1:200
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100. For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRRX1

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns.

Alternate Names

Homeobox protein PHOX1, paired mesoderm homeo box 1, paired mesoderm homeobox 1 isoform pmx-1b, paired mesoderm homeobox protein 1, paired related homeobox 1, Paired-related homeobox protein 1, PHOX1PRX-1, PMX1PRX1

Gene Symbol

PRRX1

Additional PRRX1 Products

Product Documents for PRRX1 Antibody (CL14471)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PRRX1 Antibody (CL14471)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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