CD162, also known as p-selectin glycoprotein ligand-1 (PSGL-1), is a 120 - 220 kDa, mucin-like type I transmembrane glycoprotein. CD162 binds to CD62P (P-Selectin), CD62E (E-Selectin) and CD62L (L-Selectin). The interactions between P-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) mediate the earliest "rolling" of leukocytes on the lumenal surface of activated endothelium, and the interaction between leukocytes and activated platelets or other leukocytes found at sites of inflammation. CD162 is expressed on neutrophils, monocytes, and most lymphocytes including NK and T cells but PSGL-1 stains B cells at significantly lower levels than other cell types.

Long Name

P-Selectin Glycoprotein Ligand 1

Alternate Names

CD162, PSGL1, SELPLG

Gene Symbol

SELPLG

Additional PSGL-1/CD162 Products

Product Documents for PSGL-1/CD162 Antibody (PSGL1/8135R) [Janelia Fluor® 646]

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Product Specific Notices for PSGL-1/CD162 Antibody (PSGL1/8135R) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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PSGL-1/CD162 Antibody (PSGL1/8135R) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20931JF646

Key Product Details

Species Reactivity

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Product Specifications

Immunogen

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Applications for PSGL-1/CD162 Antibody (PSGL1/8135R) [Janelia Fluor® 646]

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

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Background: PSGL-1/CD162