PSMB5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13820

Novus Biologicals, part of Bio-Techne
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NBP2-13820-25ul
NBP2-13820
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (90%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PSMB5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGST

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PSMB5 Antibody

Western Blot: PSMB5 Antibody [NBP2-13820]

Western Blot: PSMB5 Antibody [NBP2-13820]

Western Blot: PSMB5 Antibody [NBP2-13820] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Hep-G2
Immunocytochemistry/ Immunofluorescence: PSMB5 Antibody [NBP2-13820]

Immunocytochemistry/ Immunofluorescence: PSMB5 Antibody [NBP2-13820]

Immunocytochemistry/Immunofluorescence: PSMB5 Antibody [NBP2-13820] - Staining of human cell line PC-3 shows localization to nucleoplasm. Antibody staining is shown in green.
PSMB5 Antibody

Immunohistochemistry-Paraffin: PSMB5 Antibody [NBP2-13820] -

Immunohistochemistry-Paraffin: PSMB5 Antibody [NBP2-13820] - Staining of human cerebellum shows strong nuclear positivity in cells in granular layer.
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Applications for PSMB5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PSMB5

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit).

Long Name

Proteasome subunit beta type-5

Alternate Names

LMPX, MB1, Proteasome chain 6

Gene Symbol

PSMB5

Additional PSMB5 Products

Product Documents for PSMB5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PSMB5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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