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PTGER2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-02375

Novus Biologicals, part of Bio-Techne
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NBP1-02375

Key Product Details

Species Reactivity

Human, Monkey, Primate

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from 2nd cytoplasmic domain of human PTGER2.

Epitope

2nd cytoplasmic domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Rat (88%), Sheep (88%), Bovine (88%), Equine (88%), Canine (81%), Hamster (81%).

Specificity

Human EP2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PTGER4 (50%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PTGER2 Antibody - BSA Free

Immunohistochemistry-Paraffin: PTGER2 Antibody - BSA Free [NBP1-02375]

Immunohistochemistry-Paraffin: PTGER2 Antibody - BSA Free [NBP1-02375]

Immunohistochemistry-Paraffin: PTGER2 Antibody - BSA Free [NBP1-02375] - Staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 40 ug/ml.

Applications for PTGER2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Paraffin

10-20 ug/ml
Application Notes
IHC: NBP1-02375 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PTGER2

Prostaglandin E Receptor EP2 is a member of the Prostanoid Receptor subfamily. Along with several other receptor subtypes (EP1, EP3, and EP4), it mediates the diverse biological effects of Prostaglandin E2 (PGE2). PGE2 has been implicated in numerous processes, including immune response modulation, male erectile function, induction of labor, cervical cancer, control of blood pressure, asthma, and more recently, Alzheimer's Disease.

Long Name

Prostaglandin E2 Receptor 2, Subtype EP2

Alternate Names

EP2

Entrez Gene IDs

5732 (Human)

Gene Symbol

PTGER2

UniProt

Additional PTGER2 Products

Product Documents for PTGER2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTGER2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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