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PTH1R/PTHR1 Antibody (1G7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26359

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26359-100ul
NBP3-26359-50ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1G7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for PTH1R/PTHR1 Antibody (1G7)

Immunogen

A synthesized peptide derived from Human PTH1R/PTHR1 [UniProt Q03431]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTH1R/PTHR1 Antibody (1G7)

PTH1R/PTHR1 Antibody (1G7)

Western Blot: PTH1R/PTHR1 Antibody (1G7) [NBP3-26359] -

Western Blot: PTH1R/PTHR1 Antibody (1G7) [NBP3-26359] - Positive Western Blot detected in: U-251 whole cell lysate, THP-1 whole cell lysate, Ntera-2 whole cell lysate.
All lanes: PTH1R/PTHR1 Antibody at 1: 1000
Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.
Predicted band size: 67 kDa
Observed band size: 72, 55 kDa

Applications for PTH1R/PTHR1 Antibody (1G7)

Application
Recommended Usage

Western Blot

1:500-1:5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: PTH1R/PTHR1

PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR. PTHR1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus. ESTs have been isolated from B-cell/lung/testis, brain, breast, fetus, heart, heart/melanocyte/uterus, kidney, liver/spleen, lung, placenta, and testis libraries.

Long Name

Parathyroid Hormone Receptor 1

Alternate Names

PTHR, PTHR1

Gene Symbol

PTH1R

Additional PTH1R/PTHR1 Products

Product Documents for PTH1R/PTHR1 Antibody (1G7)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTH1R/PTHR1 Antibody (1G7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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