PTH1R/PTHR1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS761

Novus Biologicals, part of Bio-Techne
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NLS761
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Key Product Details

Species Reactivity

Validated:

Human, Monkey

Predicted:

Bovine (95%), Orangutan (90%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all PTH1R/PTHR1 Antibodies »

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from N-terminal extracellular domain of human PTH1R/PTHR1.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Marmoset (100%), Gorilla (95%), Gibbon (95%), Equine (85%), Rabbit (80%).

Localization

Membrane; multi pass membrane protein.

Specificity

Human PTH1R/PTHR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except UHRF1BP1 (40%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PTH1R/PTHR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: PTH1R/PTHR1 Antibody - BSA Free [NLS761]

Immunohistochemistry-Paraffin: PTH1R/PTHR1 Antibody - BSA Free [NLS761]

Immunohistochemistry-Paraffin: PTH1R/PTHR1 Antibody [NLS761] - Human Bone, Giant Cell Tumor. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: PTH1R/PTHR1 Antibody - BSA Free [NLS761]

Immunohistochemistry-Paraffin: PTH1R/PTHR1 Antibody - BSA Free [NLS761]

Immunohistochemistry-Paraffin: PTH1R/PTHR1 Antibody [NLS761] - Analysis of anti-PTH1R antibody with human kidney, renal tubules at 2 ug/ml.

Applications for PTH1R/PTHR1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

2-4 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PTH1R/PTHR1

PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR. PTHR1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus. ESTs have been isolated from B-cell/lung/testis, brain, breast, fetus, heart, heart/melanocyte/uterus, kidney, liver/spleen, lung, placenta, and testis libraries.

Long Name

Parathyroid Hormone Receptor 1

Alternate Names

PTHR, PTHR1

Gene Symbol

PTH1R

Additional PTH1R/PTHR1 Products

Product Documents for PTH1R/PTHR1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTH1R/PTHR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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