PTPN21 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12337

Novus Biologicals, part of Bio-Techne
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NBP3-12337
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Chicken, Primate

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PTPN21 Antibodies »

Product Summary for PTPN21 Antibody

Immunogen

Synthetic peptide taken within amino acid region 400-500 on mouse PTPND1 protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for PTPN21 Antibody

Immunohistochemistry-Paraffin: PTPN21 Antibody [NBP3-12337]

Immunohistochemistry-Paraffin: PTPN21 Antibody [NBP3-12337]

Immunohistochemistry-Paraffin: PTPN21 Antibody [NBP3-12337] - Mouse Spleen. 1:50 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.

Applications for PTPN21 Antibody

Application
Recommended Usage

ELISA

1:1000

Immunohistochemistry

1:50-1:150

Immunohistochemistry-Paraffin

1:50-1:150

Immunoprecipitation

1:200

Western Blot

1:250
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: PTPN21

PTPN21 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.

Long Name

Tyrosine-protein phosphatase non-receptor type 21

Alternate Names

PTPD1

Gene Symbol

PTPN21

Additional PTPN21 Products

Product Documents for PTPN21 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTPN21 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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