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PTPRD Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-94767

Novus Biologicals, part of Bio-Techne
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NBP2-94767-0.02ml
NBP2-94767-0.1ml

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 475-574 of human PTPRD (NP_002830.1). QITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTPRD Antibody - BSA Free

PTPRD Antibody

Immunohistochemistry: PTPRD Antibody [NBP2-94767] -

Immunohistochemistry: PTPRD Antibody [NBP2-94767] - Chronic constriction injury induces neuropathic pain and PTPRD is expressed in DRG neurons. Representative images of PTPRD co-staining with GFAP, S100 beta, or Tuj1 in DRG sections 7 days after CCI. Scale bars, 100 um. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/35493326/) licensed under a CC-BY license.
PTPRD Antibody

Western Blot: PTPRD Antibody [NBP2-94767] -

Western Blot: PTPRD Antibody [NBP2-94767] - Analysis of various lysates, using PTPRD Rabbit pAb at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
PTPRD Antibody - BSA Free

Immunohistochemistry: PTPRD Antibody - BSA Free [NBP2-94767] -

Immunohistochemistry: PTPRD Antibody - BSA Free [NBP2-94767] - Protein tyrosine phosphatase receptor type D expression levels are increased in the DRG after CCI. (A) Representative images of DRG sections stained for PTPRD (red) & Tuj1 (green) in the indicated groups. Scale bars, 100 μm. (B) Western blot of PTPRD levels in ipsilateral DRGs (L4–L5) at 0, 1, 3, 7, & 14 days after CCI. Each experiment was repeated three times. (C) Quantitative analysis of data in (B). N = 3, **p < 0.01, ***p < 0.001. (D) Western blot of PTPRD levels in contralateral DRGs (L4–L5) at 0, 1, 3, 7, & 14 days after CCI. Each experiment was repeated three times. (E) Quantitative analysis of data in (D). N = 3, p > 0.05. Statistical comparisons were performed by unpaired Student’s t-test (C,E). Image collected & cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/35493326), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Applications for PTPRD Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:100-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PTPRD

The protein encoded by the PTPRD gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple tissue specific alternatively spliced transcript variants of this gene have been reported. (provided by RefSeq)

Long Name

Protein Tyrosine Phosphatase Receptor-type delta

Alternate Names

PTP delta, PTP-delta, PTPD, PTPdelta, R-PTP-Delta, RPTP-Delta

Gene Symbol

PTPRD

Additional PTPRD Products

Product Documents for PTPRD Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTPRD Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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