QDPR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-32408

Novus Biologicals, part of Bio-Techne
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NBP2-32408
NBP2-32408-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all QDPR Antibodies »

Product Summary for QDPR Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SLAGKNSGMPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGKNRPSSGSLIQVVTTEGRTEL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for QDPR Antibody

Western Blot: QDPR Antibody [NBP2-32408]

Western Blot: QDPR Antibody [NBP2-32408]

Western Blot: QDPR Antibody [NBP2-32408] - Analysis using Anti-QDPR antibody NBP2-32408 (A) shows similar pattern to independent antibody NBP2-49455 (B).
Immunocytochemistry/ Immunofluorescence: QDPR Antibody [NBP2-32408]

Immunocytochemistry/ Immunofluorescence: QDPR Antibody [NBP2-32408]

Immunocytochemistry/Immunofluorescence: QDPR Antibody [NBP2-32408] - Immunofluorescent staining of human cell line A549 shows localization to mitochondria.
Immunohistochemistry-Paraffin: QDPR Antibody [NBP2-32408]

Immunohistochemistry-Paraffin: QDPR Antibody [NBP2-32408]

Immunohistochemistry-Paraffin: QDPR Antibody [NBP2-32408] - Staining of human hippocampus shows strong cytoplasmic positivity in glial cells.

Applications for QDPR Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: QDPR

QDPR encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Long Name

Quinoid Dihydropteridine Reductase

Alternate Names

DHPR, HDHPR, PKU2, SDR33C1

Gene Symbol

QDPR

Additional QDPR Products

Product Documents for QDPR Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for QDPR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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