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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 350 and 400 of human RAB3 GTPase activating protein subunit 1 using the numbering given in entry NP_036365.1 (GeneID 22930).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RAB3GAP1 Antibody

Western Blot: RAB3GAP1 Antibody [NBP1-19154]

Western Blot: RAB3GAP1 Antibody [NBP1-19154]

Western Blot: RAB3GAP1 Antibody [NBP1-19154] - Whole cell lysate from HeLa and 293T cells. Rab3- GAP1 was also immunoprecipitated by rabbit anti-Rab3-GAP1 antibody NBP1-19155.

Applications for RAB3GAP1 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: RAB3GAP1

Members of the RAB3 protein family (see RAB3A; MIM 179490) are implicated in regulated exocytosis of neurotransmitters and hormones. RAB3GAP, which is involved in regulation of RAB3 activity, is a heterodimeric complex consisting a 130-kD catalytic subunit and a 150-kD noncatalytic subunit (MIM 609275). RAB3GAP specifically converts active RAB3-GTP to the inactive form RAB3-GDP (Aligianis et al., 2005 [PubMed 15696165]).[supplied by OMIM]

Alternate Names

KIAA0066P130, RAB3 GTPase activating protein subunit 1 (catalytic), RAB3 GTPase-activating protein 130 kDa subunit, rab3 GTPase-activating protein catalytic subunit, Rab3-GAP, Rab3-GAP p130, RAB3GAPDKFZp434A012, WARBM1RAB3GAP130

Entrez Gene IDs

22930 (Human)

Gene Symbol

RAB3GAP1

UniProt

Additional RAB3GAP1 Products

Product Documents for RAB3GAP1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for RAB3GAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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