RAB8A Antibody (S06-8A7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19493

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19493-100ul
NBP3-19493-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S06-8A7

Concentration

0.3 mg/ml

View all RAB8A Antibodies »

Product Summary for RAB8A Antibody (S06-8A7)

Immunogen

A synthetic peptide of human RAB8A (Uniprot # P61006)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RAB8A Antibody (S06-8A7)

Western Blot: RAB8A Antibody (S06-8A7) [NBP3-19493]

Western Blot: RAB8A Antibody (S06-8A7) [NBP3-19493]

Western Blot: RAB8A Antibody (S06-8A7) [NBP3-19493] - Western blot detection of RAB8A in K562, C6, 3T3, Hela cell lysates using NBP3-19493 (1:1000 diluted). Predicted band size: 24kDa. Observed band size: 24kDa.
Immunocytochemistry/ Immunofluorescence: RAB8A Antibody (S06-8A7) [NBP3-19493]

Immunocytochemistry/ Immunofluorescence: RAB8A Antibody (S06-8A7) [NBP3-19493]

Immunocytochemistry/Immunofluorescence: RAB8A Antibody (S06-8A7) [NBP3-19493] - Immunofluorescence of RAB8A (green) in Hela cells using NBP3-19493 at dilution 1/200, and DAPI (blue)
Immunohistochemistry-Paraffin: RAB8A Antibody (S06-8A7) [NBP3-19493]

Immunohistochemistry-Paraffin: RAB8A Antibody (S06-8A7) [NBP3-19493]

Immunohistochemistry-Paraffin: RAB8A Antibody (S06-8A7) [NBP3-19493] - Immunohistochemistry of RAB8A in paraffin-embedded Human colon cancer tissue using NBP3-19493 at dilution 1/1

Applications for RAB8A Antibody (S06-8A7)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/50

Immunohistochemistry

1/50-1/200

Western Blot

1/1000-1/5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RAB8A

RAB8A is encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Long Name

Ras-related protein Rab-8A

Alternate Names

MEL, Oncogene c-mel, RAB8

Gene Symbol

RAB8A

Additional RAB8A Products

Product Documents for RAB8A Antibody (S06-8A7)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RAB8A Antibody (S06-8A7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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