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Rapsyn Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-37778

Novus Biologicals, part of Bio-Techne
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NBP1-37778

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence YQSNQTEKALQVWTK-C corresponding to N-Terminus according to NP_005046.2, NP_116034.2.

Epitope

N-Terminus

Specificity

This antibody is expected to recognize both reported isoforms (NP_005046.2; NP_116034.2).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Rapsyn Antibody

Western Blot: Rapsyn Antibody [NBP1-37778]

Western Blot: Rapsyn Antibody [NBP1-37778]

Western Blot: Rapsyn Antibody [NBP1-37778] (0.5ug/ml) staining of Human Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Rapsyn Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:128000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 38 kDa band observed in human skeletal muscle lysates (calculated MW of 39.9 kDa band according to NP_116034.2).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Rapsyn

This protein belongs to a family of proteins that are receptor associated proteins of the synapse. It contains a conserved cAMP-dependent protein kinase phosphorylation site. It is believed to play some role in anchoring or stabilizing the nicotinic acetylcholine receptor at synaptic sites. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Two splice variants have been identified for this gene.

Alternate Names

43 kDa postsynaptic protein, Acetylcholine receptor-associated 43 kDa protein, CMS1D43 kDa receptor-associated protein of the synapse, CMS1EMGC3597, RAPsyn, receptor-associated protein of the synapse, receptor-associated protein of the synapse, 43kD, RNF205RING finger protein 205

Entrez Gene IDs

5913 (Human)

Gene Symbol

RAPSN

Additional Rapsyn Products

Product Documents for Rapsyn Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Rapsyn Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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