RAR beta/NR1B2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98903

Novus Biologicals, part of Bio-Techne
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NBP2-98903-100ul
NBP2-98903-50ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all RAR beta/NR1B2 Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Mouse RAR beta/NR1B2.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for RAR beta/NR1B2 Antibody

Immunocytochemistry/ Immunofluorescence: RAR beta/NR1B2 Antibody [NBP2-98903]

Immunocytochemistry/ Immunofluorescence: RAR beta/NR1B2 Antibody [NBP2-98903]

Immunocytochemistry/Immunofluorescence: RAR beta/NR1B2 Antibody [NBP2-98903] - Immunofluorescence staining of RAR beta/NR1B2 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Mouse RAR beta/NR1B2 polyclonal antibody (dilution ratio 1:1000) at 4C overnight. Then cells were stained with the Alexa Fluor$488-conjugated Goat Anti-rabbit IgG Secondary antibody (green). Positive staining was localized to nucleus.
Immunohistochemistry-Paraffin: RAR beta/NR1B2 Antibody [NBP2-98903]

Immunohistochemistry-Paraffin: RAR beta/NR1B2 Antibody [NBP2-98903]

Immunohistochemistry-Paraffin: RAR beta/NR1B2 Antibody [NBP2-98903] - Immunochemical staining RAR beta/NR1B2 in mouse kidney with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Immunohistochemistry-Paraffin: RAR beta/NR1B2 Antibody [NBP2-98903]

Immunohistochemistry-Paraffin: RAR beta/NR1B2 Antibody [NBP2-98903]

Immunohistochemistry-Paraffin: RAR beta/NR1B2 Antibody [NBP2-98903] - Immunochemical staining RAR beta/NR1B2 in human breast carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
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Applications for RAR beta/NR1B2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:300-1:10000

Immunohistochemistry-Paraffin

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RAR beta/NR1B2

Retinoids can reverse various premalignant lesions as well as prevent some second primary tumors. The effects of retinoids are regulated by retinoic acid receptors (RAR) and retinoid X receptors, which act as ligand-activated transcription factors. Ligand-dependent transcriptional activation of RARs is a multistep process that ends with the formation of a multimeric co-activator complex on regulated promoters (1,2). Loss of RAR-beta expression and the accumulation of p53 and Ki67 proteins may help in the early identification of esophageal cancer in high-risk populations (3).

Long Name

Retinoic Acid Receptor, beta

Alternate Names

HAP, NR1B2, RARB, RRB2

Gene Symbol

RARB

Additional RAR beta/NR1B2 Products

Product Documents for RAR beta/NR1B2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RAR beta/NR1B2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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