RASGRP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86661

Novus Biologicals, part of Bio-Techne
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NBP1-86661
NBP1-86661-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RASGRP2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DDSGKVRDPQLVRMFLMMHPWYIPSSQLAAKLLHIYQQSRKDNSNSLQVKTCHLVRYWISAFPAEFDLNPELAEQIKELKALLDQEGNRRHSSLIDIDSVPTYKWKRQVTQRNPV

Reactivity Notes

Reactivity reported in scientific literature (PMID: 25541736)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RASGRP2 Antibody

Western Blot: RASGRP2 Antibody [NBP1-86661]

Western Blot: RASGRP2 Antibody [NBP1-86661]

Western Blot: RASGRP2 Antibody [NBP1-86661] - Analysis in human cell line NB4.
Immunohistochemistry-Paraffin: RASGRP2 Antibody [NBP1-86661]

Immunohistochemistry-Paraffin: RASGRP2 Antibody [NBP1-86661]

Immunohistochemistry-Paraffin: RASGRP2 Antibody [NBP1-86661] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

Applications for RASGRP2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

0.04 - 0.4 ug/ml
Application Notes
IHC reported in scientific literature (PMID: 25541736). For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RASGRP2

FABP7 is encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternate Names

Calcium and DAG-regulated guanine nucleotide exchange factor I, CalDAG-GEFI, CDC25Lcalcium and diacylglycerol-regulated guanine nucleotide exchange factor I, Cdc25-like protein, F25B3.3 kinase-like protein, guanine exchange factor MCG7, hCDC25L, MCG7, RAS guanyl nucleotide-releasing protein 2, RAS guanyl releasing protein 2 (calcium and DAG-regulated), RAS guanyl-releasing protein 2

Gene Symbol

RASGRP2

Additional RASGRP2 Products

Product Documents for RASGRP2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RASGRP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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