RCOR1/CoREST Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38720

Novus Biologicals, part of Bio-Techne
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NBP2-38720
NBP2-38720-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RCOR1/CoREST Antibodies »

Product Summary for RCOR1/CoREST Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SSDEEHGGGGMRVGPQYQAVVPDFDPAKLARRSQERDNLGMLV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RCOR1/CoREST Antibody

Immunocytochemistry/ Immunofluorescence: RCOR1/CoREST Antibody [NBP2-38720]

Immunocytochemistry/ Immunofluorescence: RCOR1/CoREST Antibody [NBP2-38720]

Immunocytochemistry/Immunofluorescence: RCOR1/CoREST Antibody [NBP2-38720] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: RCOR1/CoREST Antibody [NBP2-38720]

Immunohistochemistry-Paraffin: RCOR1/CoREST Antibody [NBP2-38720]

Immunohistochemistry-Paraffin: RCOR1/CoREST Antibody [NBP2-38720] - Staining of human testis shows strong nuclear positivity in subset of cells in seminiferus ducts.

Applications for RCOR1/CoREST Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RCOR1/CoREST

Brain type II sodium channels are important in neuronal phenotyping and are only seen at high levels in neurons. Studies have shown that CoREST functions as a corepressor for REST. This interaction between REST and CoREST is accomplished by means of a single zinc finger binding motif originating from REST. Together, the REST-CoREST complex mediates long term repression of the type II sodium channel gene (1).

Long Name

REST Corepressor 1

Alternate Names

CoREST, RCOR1

Gene Symbol

RCOR1

UniProt

Q9UKL0 (Human)

Additional RCOR1/CoREST Products

Product Documents for RCOR1/CoREST Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RCOR1/CoREST Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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