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Red Blood Cells Antibody (34-3C)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11200

Novus Biologicals, part of Bio-Techne
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NBP3-11200

Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 34-3C

Concentration

0.1 mg/ml

Product Specifications

Immunogen

RBC

Epitope

The monoclonal antibody 34-3C recognizes an exposed surface determinant of intact red blood cells (RBC).

Specificity

The monoclonal antibody only recognises antigenic determinants expressed on Mouse RBC and not on other species of RBC.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Endotoxin Level

<24 EU/mg

Applications for Red Blood Cells Antibody (34-3C)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
For Flow Cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

0.2 um filtered solution in PBS, 0.1% BSA

Preservative

No Preservative

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Red Blood Cells

The monoclonal antibody 34-3C recognizes an exposed surface determinant of intact red blood cells (RBC). The high-affinity anti-RBC monoclonal antibody efficiently bind to Fc receptors on macrophages inducing anemia in vivo due to a rapid Fc receptor (FcyR)-mediated erythrophagocytosis of opsonised RBC in spleen and livers. The capacity of the antibody to interact with FcyR is responsible for its haemolytic activity. The monoclonal antibody only recognises antigenic determinants expressed on Mouse RBC and not on other species of RBC.

Alternate Names

Erythrocytes, Erythroid Cells, Haematids, RBC

Additional Red Blood Cells Products

Product Documents for Red Blood Cells Antibody (34-3C)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Red Blood Cells Antibody (34-3C)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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