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Relaxin-1 Antibody (1H6)

Novus Biologicals, part of Bio-Techne | Catalog # H00006013-M01

Novus Biologicals, part of Bio-Techne
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H00006013-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunoprecipitation, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1H6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

RLN1 (AAH05956.1, 27 a.a. ~ 185 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. WKDDVIKLCGRELVRAQIAICGMSTWSKRSLSQEDAPQTPRPVAEIVPSFINKDTETIIIMLEFIANLPPELKAALSERQPSLPELQQYVPALKDSNLSFEEFKKLIRNRQSEAADSNPSELKYLGLDTHSQKKRRPYVALFEKCCLIGCTKRSLAKYC

Specificity

relaxin 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Relaxin-1 Antibody (1H6)

Immunoprecipitation: Relaxin-1 Antibody (1H6) [H00006013-M01]

Immunoprecipitation: Relaxin-1 Antibody (1H6) [H00006013-M01]

Immunoprecipitation: Relaxin-1 Antibody (1H6) [H00006013-M01] - Analysis of RLN1 transfected lysate using anti-RLN1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with RLN1 MaxPab rabbit polyclonal antibody.
Sandwich ELISA: Relaxin-1 Antibody (1H6) [H00006013-M01] - Detection limit for recombinant GST tagged RLN1 is approximately 10ng/ml as a capture antibody.

Applications for Relaxin-1 Antibody (1H6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Relaxin-1

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds; however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.

Alternate Names

H1, Relaxin1, RLN1, RLXH1

Entrez Gene IDs

6013 (Human)

Gene Symbol

RLN1

OMIM

179730 (Human)

Additional Relaxin-1 Products

Product Documents for Relaxin-1 Antibody (1H6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Relaxin-1 Antibody (1H6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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