Renin Antibody (SR1820)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22259

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22259-100ul
NBP3-22259-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1820

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Renin Antibodies »

Product Summary for Renin Antibody (SR1820)

Immunogen

A synthesized peptide derived from human Renin (Uniprot #: P00797)

Specificity

Detects endogenous levels of total Renin

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Renin Antibody (SR1820)

Western Blot: Renin Antibody (SR1820) [NBP3-22259] -

Western Blot: Renin Antibody (SR1820) [NBP3-22259] - Western blot analysis using NBP3-22259 in K562 cell lysate.

Applications for Renin Antibody (SR1820)

Application
Recommended Usage

Flow Cytometry

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Renin

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.

Alternate Names

Angiotensinogenase, REN

Gene Symbol

REN

Additional Renin Products

Product Documents for Renin Antibody (SR1820)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Renin Antibody (SR1820)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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