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REPS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80891

Novus Biologicals, part of Bio-Techne
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NBP1-80891
NBP1-80891-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YPLPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLN

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (83%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for REPS2 Antibody

Immunohistochemistry: REPS2 Antibody [NBP1-80891]

Immunohistochemistry: REPS2 Antibody [NBP1-80891]

Immunohistochemistry: REPS2 Antibody [NBP1-80891] - DKK-1 induces ALDH1A1, REPS2 and AKR1C3 genes involved in chemotherapy detoxification. Immunohistochemical analysis of ALDH1A1, REPS2 and AKR1C3 expression in representative nuclear DKK-1-positive (strong staining) and -negative (weak staining) tumors. Scale bars: 50 um. Image collected and cropped by CiteAb from the following publication (https://www.oncotarget.com/fulltext/3464), licensed under a CC-BY license.
Immunohistochemistry-Paraffin: REPS2 Antibody [NBP1-80891]

Immunohistochemistry-Paraffin: REPS2 Antibody [NBP1-80891]

Immunohistochemistry-Paraffin: REPS2 Antibody [NBP1-80891] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in glial cells.

Applications for REPS2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:50-1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF and IHC reported in (PMID: 25788273).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: REPS2

The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

partner of Ral-binding protein 1, POB1Partner of RalBP1, RALBP1 associated Eps domain containing 2, ralBP1-associated Eps domain-containing protein 2, RalBP1-interacting protein 2

Entrez Gene IDs

9185 (Human)

Gene Symbol

REPS2

Additional REPS2 Products

Product Documents for REPS2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for REPS2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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