Respiratory Syncytial Virus Antibody (8B10cc)

Novus Biologicals, part of Bio-Techne | Catalog # NB120-10016

Novus Biologicals, part of Bio-Techne
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NB120-10016-0.2mg
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Key Product Details

Species Reactivity

Validated:

Virus

Applications

ELISA, Lateral Flow Assay

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 8B10cc

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Respiratory Syncytial Virus Antibodies »

Product Summary for Respiratory Syncytial Virus Antibody (8B10cc)

Immunogen

Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified RSV, strain Long.

Specificity

Nucleoprotein (N) protein specific. NB120-10016 reacts only with mature virions with completely assembled nucleocapsids. It fails to reorganize the N-protein epitope of immature and destroyed virions, which indicates conformation dependence of the NB120-10016 binding site.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Respiratory Syncytial Virus Antibody (8B10cc)

Application
Recommended Usage

ELISA

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

0.09% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Respiratory Syncytial Virus

Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.

Alternate Names

Fusion glycoprotein F0, Fusion glycoprotein F1, Fusion glycoprotein F2, RS virus, RSV

Additional Respiratory Syncytial Virus Products

Product Documents for Respiratory Syncytial Virus Antibody (8B10cc)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Respiratory Syncytial Virus Antibody (8B10cc)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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