RGS14 Antibody (2F8)

Novus Biologicals, part of Bio-Techne | Catalog # H00010636-M03

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2F8

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RGS14 Antibodies »

Product Specifications

Immunogen

RGS14 (AAH14094, 1 a.a. ~ 566 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MPGKPKHLGVPNGRMVLAVSDGELSSTTGPQGQGEGRGSSLSIHSLPSGPSSPFPTEEQPVASWALSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAEGRPLREPGSSRLGSPDATRKKPKLKPGKSLPLGVEELGQLPPVEGPGGRPLRKSFRRELGGTANAALRRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSTEGESESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQALVLDQDCTVLADQEVRLENRITFELELTALERVVRISAKPTKRLQEALQPILEKHGLSPLEVVLHRPGEKQPLDLGKLVSSVAAQRLVLDTLPGVKISKARDKSPCRSQGCPPRTQDKATHPPPASPSSLVKVPSSATGKRQTCDIKGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPAQGPSSEETPPQTKSAAQPIGGSLNSTTDSAL

Specificity

Reacts with regulator of G-protein signaling 14.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for RGS14 Antibody (2F8)

Immunocytochemistry/ Immunofluorescence: RGS14 Antibody (2F8) [H00010636-M03]

Immunocytochemistry/ Immunofluorescence: RGS14 Antibody (2F8) [H00010636-M03]

Immunocytochemistry/Immunofluorescence: RGS14 Antibody (2F8) [H00010636-M03] - Analysis of monoclonal antibody to RGS14 on HeLa cell. Antibody concentration 10 ug/ml
Immunohistochemistry-Paraffin: RGS14 Antibody (2F8) [H00010636-M03]

Immunohistochemistry-Paraffin: RGS14 Antibody (2F8) [H00010636-M03]

Immunohistochemistry-Paraffin: RGS14 Antibody (2F8) [H00010636-M03] - Analysis of monoclonal antibody to RGS14 on formalin-fixed paraffin-embedded human testis. Antibody concentration 3 ug/ml
ELISA: RGS14 Antibody (2F8) [H00010636-M03]

ELISA: RGS14 Antibody (2F8) [H00010636-M03]

ELISA: RGS14 Antibody (2F8) [H00010636-M03] - Detection limit for recombinant GST tagged RGS14 is 0.1 ng/ml as a capture antibody.

Applications for RGS14 Antibody (2F8)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against recombinant protein in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: RGS14

This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]

Alternate Names

regulator of G-protein signaling 14, regulator of G-protein signalling 14

Entrez Gene IDs

10636 (Human)

Gene Symbol

RGS14

UniProt

AAH14094 (Human)

Additional RGS14 Products

Product Documents for RGS14 Antibody (2F8)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RGS14 Antibody (2F8)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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