RGS19 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41987

Novus Biologicals, part of Bio-Techne
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NBP3-41987
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all RGS19 Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human RGS19 (Uniprot#: P49795; Met1-Ala217 (Uniprot#: P49795)

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for RGS19 Antibody

RGS19 Antibody

Immunohistochemistry-Paraffin: RGS19 Antibody [NBP3-41987] -

Immunohistochemistry-Paraffin: RGS19 Antibody [NBP3-41987] - DAB staining on IHC-P; Sample: Human Stomach cancer Tissue; Primary Ab: 10ug/ml NBP3-41987; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
RGS19 Antibody

Immunohistochemistry-Paraffin: RGS19 Antibody [NBP3-41987] -

Immunohistochemistry-Paraffin: RGS19 Antibody [NBP3-41987] - DAB staining on IHC-P; Sample: Human Liver cancer Tissue; Primary Ab: 10ug/ml NBP3-41987; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
RGS19 Antibody

Immunohistochemistry-Paraffin: RGS19 Antibody [NBP3-41987] -

Immunohistochemistry-Paraffin: RGS19 Antibody [NBP3-41987] - DAB staining on IHC-P; Sample: Human Lung cancer Tissue; Primary Ab: 10ug/ml NBP3-41987; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Applications for RGS19 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.2-2ug/mL

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS, pH7.4, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RGS19

G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.; FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein. SUBCELLULAR LOCATION: Membrane; Lipid-anchor. TISSUE SPECIFICITY: Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.

Alternate Names

G alpha interacting protein, GAIPG protein signalling regulator 19, G-alpha-interacting protein, GNAI3IP, guanine nucleotide binding protein alpha inhibiting activity polypeptide 3interacting protein, regulator of G-protein signaling 19, regulator of G-protein signalling 19, RGSGAIP

Gene Symbol

RGS19

Additional RGS19 Products

Product Documents for RGS19 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RGS19 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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