RHBDD3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76250

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all RHBDD3 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 13 amino acid synthetic peptide from near the center of human RHBDD3. The immunogen is located within amino acids 170 - 220 of RHBDD3. Amino Acid Squence: FRWLEPSERRLQV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RHBDD3 Antibody - BSA Free

Western Blot: RHBDD3 AntibodyBSA Free [NBP1-76250]

Western Blot: RHBDD3 AntibodyBSA Free [NBP1-76250]

Western Blot: RHBDD3 Antibody [NBP1-76250] - Rat lung tissue lysate with RHBDD3 antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: RHBDD3 Antibody - BSA Free [NBP1-76250]

Immunocytochemistry/ Immunofluorescence: RHBDD3 Antibody - BSA Free [NBP1-76250]

Immunocytochemistry/Immunofluorescence: RHBDD3 Antibody [NBP1-76250] - Immunofluorescence of RHBDD32 in rat lung tissue with RHBDD3 antibody at 20 ug/mL.

Applications for RHBDD3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RHBDD3

The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD3 was initially identified as a novel pituitary tumor apoptosis gene (PTAG) whose expression was reduced in certain pituitary adenomas. Overexpression of RHBDD3 in AtT20 cells showed an increase in apoptotic activity and caspase activation in response to bromocriptine, and apoptosis-inducing dopamine D2 analog, suggesting that reactivation of RHBDD3 in tumors may be a therapeutically useful tool. Later experiments also showed that RHBDD3 expression is also reduced in several primary colorectal tumors, indicating that loss of RHBDD3 contributes to a blunted apoptotic response and probably predisposes cells towards malignant transformation.

Alternate Names

C22orf3, chromosome 22 open reading frame 3, HS984G1A, pituitary tumor apoptosis, PTAG, rhomboid domain containing 3, rhomboid domain-containing protein 3

Gene Symbol

RHBDD3

UniProt

NP_036397 (Human)

Additional RHBDD3 Products

Product Documents for RHBDD3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RHBDD3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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