Ribonuclease Inhibitor Antibody (OTI1B7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-03254

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI1B7

Concentration

0.66 mg/ml

View all Ribonuclease Inhibitor Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human RNH1 (NP_002930) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

49.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Ribonuclease Inhibitor Antibody (OTI1B7)

Western Blot: Ribonuclease Inhibitor Antibody (1B7) [NBP2-03254] Analysis of extracts (35ug) from 9 different cell lines by using anti-Ribonuclease Inhibitor monoclonal antibody.
Immunocytochemistry/ Immunofluorescence: Ribonuclease Inhibitor Antibody (OTI1B7) [NBP2-03254]

Immunocytochemistry/ Immunofluorescence: Ribonuclease Inhibitor Antibody (OTI1B7) [NBP2-03254]

Immunocytochemistry/Immunofluorescence: Ribonuclease Inhibitor Antibody (1B7) [NBP2-03254] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY Ribonuclease Inhibitor.
Immunohistochemistry-Paraffin: Ribonuclease Inhibitor Antibody (OTI1B7) [NBP2-03254]

Immunohistochemistry-Paraffin: Ribonuclease Inhibitor Antibody (OTI1B7) [NBP2-03254]

Immunohistochemistry-Paraffin: Ribonuclease Inhibitor Antibody (1B7) [NBP2-03254] - Staining of paraffin-embedded Human prostate tissue using anti-Ribonuclease Inhibitor mouse monoclonal antibody.
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Applications for Ribonuclease Inhibitor Antibody (OTI1B7)

Application
Recommended Usage

Flow Cytometry

1:100

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:500-2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

0.66 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Ribonuclease Inhibitor

Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM].

Alternate Names

Placental ribonuclease inhibitor, Placental RNase inhibitor, PRI, RAIMGC4569, ribonuclease inhibitor, ribonuclease/angiogenin inhibitor, ribonuclease/angiogenin inhibitor 1MGC18200, RNHMGC54054

Entrez Gene IDs

6050 (Human)

Gene Symbol

RNH1

Additional Ribonuclease Inhibitor Products

Product Documents for Ribonuclease Inhibitor Antibody (OTI1B7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Ribonuclease Inhibitor Antibody (OTI1B7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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