RIG-I Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27419

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Primate

Predicted:

Monkey (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all RIG-I Antibodies »

Product Specifications

Immunogen

A portion of amino acid 200-250 of human RIG-I was used as the immunogen.

Reactivity Notes

The amino acid sequence used as immunogen for the RIG-I antibody is 82% homologous in Rat.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RIG-I Antibody - BSA Free

Western Blot: RIG-I AntibodyBSA Free [NBP2-27419]

Western Blot: RIG-I AntibodyBSA Free [NBP2-27419]

Western Blot: RIG-I Antibody [NBP2-27419] - Analysis of 293 lysate in the 1) absence and 2) presence of immunizing peptide using RIG-I antibody at 3 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Immunohistochemistry-Paraffin: RIG-I Antibody - BSA Free [NBP2-27419]

Immunohistochemistry-Paraffin: RIG-I Antibody - BSA Free [NBP2-27419]

Immunohistochemistry-Paraffin: RIG-I Antibody [NBP2-27419] - Formalin-fixed, paraffin-embedded human breast stained with RIG-I antibody at 10 ug/ml.
Immunohistochemistry-Paraffin: RIG-I Antibody - BSA Free [NBP2-27419]

Immunohistochemistry-Paraffin: RIG-I Antibody - BSA Free [NBP2-27419]

Immunohistochemistry-Paraffin: RIG-I Antibody [NBP2-27419] - Formalin-fixed, paraffin-embedded human uterus stained with RIG-I antibody at 10 ug/ml.

Applications for RIG-I Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

5-10ug/ml

Western Blot

2-4ug/ml~

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

0.1 ml PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RIG-I

RIG-I belongs to the Helicase family and contains two CARD domains, one helicase ATP-binding domain and one helicase C-terminal domain. It is involved in innate immune defense against viruses. It triggers a transduction cascade involving MAVS/IPS1 which leads to activation of NF-kappa-B, IRF3 and IRF7 inducing expression of antiviral cytokines such as INF-beta and RANTES (CCL5) during viral replication. Reports also says that TLR3 and RIG-like receptor on myeloid dendritic cells and Rig-like receptor on human Nk cells are both required for production of IFN-gamma in response to double-stranded RNA during viral infection.

Long Name

RIG-I

Alternate Names

DDX58, RIGI

Gene Symbol

RIGI

UniProt

O95786

Additional RIG-I Products

Product Documents for RIG-I Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RIG-I Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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