Rit2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-68932

Novus Biologicals, part of Bio-Techne
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NBP2-68932
NBP2-68932-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Rit2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MEVENEASCSPGSASGGSREYKVVM

Reactivity Notes

Mouse 88%, Rat 84%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Rit2 Antibody

Immunohistochemistry-Paraffin: Rit2 Antibody [NBP2-68932]

Immunohistochemistry-Paraffin: Rit2 Antibody [NBP2-68932]

Immunohistochemistry-Paraffin: Rit2 Antibody [NBP2-68932] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry: Rit2 Antibody [NBP2-68932]

Immunohistochemistry: Rit2 Antibody [NBP2-68932]

Immunohistochemistry: Rit2 Antibody [NBP2-68932] - Immunohistochemical staining of human cerebellum shows moderate membraneous positivity in molecular layer.
Immunohistochemistry-Paraffin: Rit2 Antibody [NBP2-68932]

Immunohistochemistry-Paraffin: Rit2 Antibody [NBP2-68932]

Immunohistochemistry-Paraffin: Rit2 Antibody [NBP2-68932] - Staining of human adrenal gland shows weak to moderate cytoplasmic positivity in glandular cells.
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Applications for Rit2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
Recommended conditions for IHC,Retrieval method: HIER pH6

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Rit2

RIT2 is a gene that codes for a protein which binds and exchanges GTP and GDP, and has two isoforms with lengths of 217 and 153 amino acids, with weights of approximately 25 and 17 kDa, respectively. Current studies are being done on diseases and disorders relating to this gene including neuronitis, ehrlichiosis, cryoglobulinemia, hepatitis, Parkinson's disease, and schizophrenia. RIT2 has been shown to have interactions with CALM1, CALM2, CALM3, RLF, and HRAS in pathways such as the Trk receptor signaling, signaling to NGF, and signaling to ERKs pathways.

Long Name

Ras-like without CAAX 2

Alternate Names

RIBA, RIN, ROC2

Gene Symbol

RIT2

Additional Rit2 Products

Product Documents for Rit2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Rit2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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