Rit2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25106

Novus Biologicals, part of Bio-Techne
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NBP3-25106
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Rit2 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein Rit2 using the following amino acid sequence: LVREIRKKESMPSLMEKKLKRKDSLWKKLKGSLKKKR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Rit2 Antibody

Rit2 Antibody Immunocytochemistry/Immunofluorescence: Rit2 Antibody [NBP3-25106]

Immunocytochemistry/Immunofluorescence: Rit2 Antibody [NBP3-25106]

Staining of human cell line U2OS shows localization to nucleoplasm & cytosol.

Applications for Rit2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Rit2

RIT2 is a gene that codes for a protein which binds and exchanges GTP and GDP, and has two isoforms with lengths of 217 and 153 amino acids, with weights of approximately 25 and 17 kDa, respectively. Current studies are being done on diseases and disorders relating to this gene including neuronitis, ehrlichiosis, cryoglobulinemia, hepatitis, Parkinson's disease, and schizophrenia. RIT2 has been shown to have interactions with CALM1, CALM2, CALM3, RLF, and HRAS in pathways such as the Trk receptor signaling, signaling to NGF, and signaling to ERKs pathways.

Long Name

Ras-like without CAAX 2

Alternate Names

RIBA, RIN, ROC2

Gene Symbol

RIT2

Additional Rit2 Products

Product Documents for Rit2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Rit2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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