RKIP/PBP Antibody (1D3-1B6)

Novus Biologicals, part of Bio-Techne | Catalog # H00005037-M02

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1D3-1B6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RKIP Antibodies »

Product Specifications

Immunogen

PBP (AAH31102, 1 a.a. ~ 187 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKVLTPTQVKNRPTSISWDGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKLYEQLSGK

Localization

Cytoplasmic

Specificity

PBP - prostatic binding protein

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for RKIP/PBP Antibody (1D3-1B6)

Western Blot: RKIP/PBP Antibody (1D3-1B6) [H00005037-M02]

Western Blot: RKIP/PBP Antibody (1D3-1B6) [H00005037-M02]

Western Blot: RKIP/PBP Antibody (1D3-1B6) [H00005037-M02] - PBP monoclonal antibody (M02), clone 1D3-1B6 Analysis of PBP expression in HL-60.
Sandwich ELISA: RKIP/PBP Antibody (1D3-1B6) [H00005037-M02] - Detection limit for recombinant GST tagged PBP is approximately 0.3ng/ml as a capture antibody.

Applications for RKIP/PBP Antibody (1D3-1B6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: RKIP

PBP, also known as RKIP (RAF kinase inhibitor protein), binds ATP, opioids and phosphatidylethanolamine. PBP is able to regulate Aurora kinase B expression and the spindle checkpoint through interaction with the RAF1/MEK/ERK cascade. PBP is able to bind to RAF1 and MEK and competitively disrupt the interaction between these proteins. PBP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. It increases the production of choline acetyltransferase but not acetylcholinesterase. PBP has been implicated as a suppressor of metastasis.

Long Name

Raf kinase inhibitory protein

Alternate Names

HCNPpp, Neuropolypeptide h3, PBP, PEBP-1, PEBP1

Entrez Gene IDs

5037 (Human)

Gene Symbol

PEBP1

OMIM

604591 (Human)

UniProt

AAH31102 (Human)

Additional RKIP Products

Product Documents for RKIP/PBP Antibody (1D3-1B6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RKIP/PBP Antibody (1D3-1B6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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