RKIP/PBP Antibody (4B11) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59494

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 4B11

Format

BSA Free

Concentration

1 mg/ml

View all RKIP Antibodies »

Product Summary for RKIP/PBP Antibody (4B11) - BSA Free

Immunogen

Recombinant human RKIP/PBP (1-187aa) purified from E. coli

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for RKIP/PBP Antibody (4B11) - BSA Free

Western Blot: RKIP/PBP Antibody (4B11)BSA Free [NBP2-59494]

Western Blot: RKIP/PBP Antibody (4B11)BSA Free [NBP2-59494]

Western Blot: RKIP/PBP Antibody (4B11) [NBP2-59494] - Lane 1: HeLa cell lysates, Lane 2: SKOV3 cell lysates, Lane 3: A549 cell lysates, Lane 4: HepG2 cell lysates, Lane 5: MCF7 cell lysates, Lane 6: K562 cell lysates, Lane 7: LnCap cell lysates, Lane 8: Ramos cell lysates
Immunocytochemistry/ Immunofluorescence: RKIP/PBP Antibody (4B11) - BSA Free [NBP2-59494]

Immunocytochemistry/ Immunofluorescence: RKIP/PBP Antibody (4B11) - BSA Free [NBP2-59494]

Immunocytochemistry/Immunofluorescence: RKIP/PBP Antibody (4B11) [NBP2-59494] - Analysis of PEBP1 in HeLa cells line, monoclonal anti-human PEBP1 antibody (1:100) stained with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

Applications for RKIP/PBP Antibody (4B11) - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4), 10% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RKIP

PBP, also known as RKIP (RAF kinase inhibitor protein), binds ATP, opioids and phosphatidylethanolamine. PBP is able to regulate Aurora kinase B expression and the spindle checkpoint through interaction with the RAF1/MEK/ERK cascade. PBP is able to bind to RAF1 and MEK and competitively disrupt the interaction between these proteins. PBP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. It increases the production of choline acetyltransferase but not acetylcholinesterase. PBP has been implicated as a suppressor of metastasis.

Long Name

Raf kinase inhibitory protein

Alternate Names

HCNPpp, Neuropolypeptide h3, PBP, PEBP-1, PEBP1

Gene Symbol

PEBP1

Additional RKIP Products

Product Documents for RKIP/PBP Antibody (4B11) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RKIP/PBP Antibody (4B11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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