RKIP/PBP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89711

Novus Biologicals, part of Bio-Techne
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NBP1-89711
NBP1-89711-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RKIP Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PTQVKNRPTSISWDGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKLY

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RKIP/PBP Antibody

Immunohistochemistry-Paraffin: RKIP/PBP Antibody [NBP1-89711]

Immunohistochemistry-Paraffin: RKIP/PBP Antibody [NBP1-89711]

Immunohistochemistry-Paraffin: RKIP/PBP Antibody [NBP1-89711] - Analysis in human adrenal gland and lymph node tissues. Corresponding PEBP1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: RKIP/PBP Antibody [NBP1-89711]

Immunohistochemistry-Paraffin: RKIP/PBP Antibody [NBP1-89711]

Immunohistochemistry-Paraffin: RKIP/PBP Antibody [NBP1-89711] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: RKIP/PBP Antibody [NBP1-89711]

Immunohistochemistry-Paraffin: RKIP/PBP Antibody [NBP1-89711]

Immunohistochemistry-Paraffin: RKIP/PBP Antibody [NBP1-89711] - Staining of human adrenal gland shows very strong cytoplasmic positivity in glandular cells.
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Applications for RKIP/PBP Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RKIP

PBP, also known as RKIP (RAF kinase inhibitor protein), binds ATP, opioids and phosphatidylethanolamine. PBP is able to regulate Aurora kinase B expression and the spindle checkpoint through interaction with the RAF1/MEK/ERK cascade. PBP is able to bind to RAF1 and MEK and competitively disrupt the interaction between these proteins. PBP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. It increases the production of choline acetyltransferase but not acetylcholinesterase. PBP has been implicated as a suppressor of metastasis.

Long Name

Raf kinase inhibitory protein

Alternate Names

HCNPpp, Neuropolypeptide h3, PBP, PEBP-1, PEBP1

Gene Symbol

PEBP1

Additional RKIP Products

Product Documents for RKIP/PBP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RKIP/PBP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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