RNF7 Antibody (SR4316)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27845

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27845-100ul
NBP3-27845-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR4316

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all RNF7 Antibodies »

Product Summary for RNF7 Antibody (SR4316)

Immunogen

A synthesized peptide derived from human RNF7 (Uniprot #: Q9UBF6)

Specificity

Detects endogenous levels of total RNF7

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

13 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RNF7 Antibody (SR4316)

Western Blot: RNF7 Antibody (SR4316) [NBP3-27845] -

Western Blot: RNF7 Antibody (SR4316) [NBP3-27845] - Western blot analysis of RNF7 expression in HepG2 cell lysate.

Applications for RNF7 Antibody (SR4316)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RNF7

RNF7 is encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternate Names

CKBBP1zinc RING finger protein SAG, CKII beta-binding protein 1, Rbx2, Regulator of cullins 2, ring finger protein 7rbx2, ROC2RING-box protein 2, SAGsensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2, Sensitive to apoptosis gene protein

Gene Symbol

RNF7

Additional RNF7 Products

Product Documents for RNF7 Antibody (SR4316)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RNF7 Antibody (SR4316)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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