RNPS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92343

Novus Biologicals, part of Bio-Techne
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NBP1-92343
NBP1-92343-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RNPS1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RNPS1 Antibody

Immunocytochemistry/ Immunofluorescence: RNPS1 Antibody [NBP1-92343]

Immunocytochemistry/ Immunofluorescence: RNPS1 Antibody [NBP1-92343]

Immunocytochemistry/Immunofluorescence: RNPS1 Antibody [NBP1-92343] - Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: RNPS1 Antibody [NBP1-92343]

Immunohistochemistry-Paraffin: RNPS1 Antibody [NBP1-92343]

Immunohistochemistry-Paraffin: RNPS1 Antibody [NBP1-92343] - Staining of human hippocampus shows strong nuclear positivity in neuronal cells.
RNPS1 Antibody

Western Blot: RNPS1 Antibody [NBP1-92343] -

Western Blot: RNPS1 Antibody [NBP1-92343] - Analysis in human cell line NTERA-2.

Applications for RNPS1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RNPS1

RNPS1 encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq]

Alternate Names

E5.1, LDC2, MGC117332, RNA binding protein S1, serine-rich domain, RNA-binding protein S1, serine-rich domain, RNA-binding protein with serine-rich domain 1, SR protein, SR-related protein LDC2

Gene Symbol

RNPS1

Additional RNPS1 Products

Product Documents for RNPS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for RNPS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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