RSK1 [p Ser380] Antibody (S05-7F3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20065

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-20065-100ul
NBP3-20065-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S05-7F3

Concentration

0.3 mg/ml

View all RSK1 Antibodies »

Product Specifications

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser380 of human RSK1 (Uniprot # Q15418)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

90 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RSK1 [p Ser380] Antibody (S05-7F3)

Western Blot: RSK1 [p Ser380] Antibody (S05-7F3) [NBP3-20065] - Western blot detection of RSK1 (phospho-Ser380) in CHO-K1 cell lysates using NBP3-20065 (1:1000 diluted). Predicted band size: 83kDa. Observed band size: 83kDa.

Applications for RSK1 [p Ser380] Antibody (S05-7F3)

Application
Recommended Usage

Western Blot

1/2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RSK1

Rsk-1 (p90-Rsk-1) is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes Rsk-1, Rsk-2 and Rsk-3. These are broadly expressed serine/threonine protein kinases (1) activated in response to mitogenic stimuli, including extracellular signal-regulated protein kinases Erk1 and Erk2 (2). p90-Rsk-1 is activated by MAPK in vitro and in vivo via phosphorylation (3). Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB (2,4).

Long Name

Ribosomal Protein S6 Kinase I

Alternate Names

HU-1, MAPKAPL1A, RPS6KA1

Gene Symbol

RPS6KA1

Additional RSK1 Products

Product Documents for RSK1 [p Ser380] Antibody (S05-7F3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for RSK1 [p Ser380] Antibody (S05-7F3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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