RSK4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87108

Novus Biologicals, part of Bio-Techne
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NBP1-87108
NBP1-87108-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RSK4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PFKPASGKPDDTFCFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGNAAQFGEVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for RSK4 Antibody

Immunocytochemistry/ Immunofluorescence: RSK4 Antibody [NBP1-87108]

Immunocytochemistry/ Immunofluorescence: RSK4 Antibody [NBP1-87108]

Immunocytochemistry/Immunofluorescence: RSK4 Antibody [NBP1-87108] - Staining of human cell line RH-30 shows localization to nucleoli fibrillar center & mitochondria. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: RSK4 Antibody [NBP1-87108]

Immunohistochemistry-Paraffin: RSK4 Antibody [NBP1-87108]

Immunohistochemistry-Paraffin: RSK4 Antibody [NBP1-87108] - Staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells.

Applications for RSK4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RSK4

RSK4 is a member of the family of 90-kDa ribosomal S6 kinases (1). These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters (2). RSK4 is most abundantly expressed in brain and kidney. The predicted protein of 746 amino acids shows a high level of homology to three previously isolated members of the human RSK family. RSK2 is involved in Coffin-Lowry syndrome and nonspecific MRX. The localization of RSK4 in the interval that is commonly deleted in mentally retarded males together with the high degree of amino acid identity with RSK2 suggests that RSK4 plays a role in normal neuronal development (3).

Long Name

Ribosomal Protein S6 Kinase IV

Alternate Names

RPS6KA6

Gene Symbol

RPS6KA6

Additional RSK4 Products

Product Documents for RSK4 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RSK4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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