S-arrestin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55126

Novus Biologicals, part of Bio-Techne
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NBP2-55126
NBP2-55126-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all S-arrestin Antibodies »

Product Summary for S-arrestin Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EPNHVIFKKISRDKSVTIYLGNRDYIDHVSQVQPVDGVVLVDPDLVKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLYFSRVQVYPPVGAASTPTKLQESLLKKLGSNTYPFLLTFPDYLPCSVMLQPAPQDSGKS

Reactivity Notes

Mouse 89%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for S-arrestin Antibody

Immunohistochemistry-Paraffin: S-arrestin Antibody [NBP2-55126]

Immunohistochemistry-Paraffin: S-arrestin Antibody [NBP2-55126]

Immunohistochemistry-Paraffin: S-arrestin Antibody [NBP2-55126] - Staining of human tonsil shows no positivity in non-germinal center cells as expected.
Immunohistochemistry-Paraffin: S-arrestin Antibody [NBP2-55126]

Immunohistochemistry-Paraffin: S-arrestin Antibody [NBP2-55126]

Immunohistochemistry-Paraffin: S-arrestin Antibody [NBP2-55126] - Staining of human retina shows strong positivity in rod segments.
Immunohistochemistry-Paraffin: S-arrestin Antibody [NBP2-55126]

Immunohistochemistry-Paraffin: S-arrestin Antibody [NBP2-55126]

Immunohistochemistry-Paraffin: S-arrestin Antibody [NBP2-55126] - Staining of human duodenum shows no positivity in glandular cells as expected.
View 1 more images

Applications for S-arrestin Antibody

Application
Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: S-arrestin

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. (provided by RefSeq)

Alternate Names

arrestin 1, RP47,48 kDa protein, S-antigen; retina and pineal gland (arrestin), S-arrestin, visual arrestin

Gene Symbol

SAG

Additional S-arrestin Products

Product Documents for S-arrestin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for S-arrestin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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