S100A6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB110-93274

Novus Biologicals, part of Bio-Techne
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NB110-93274
NB110-93274SS
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all S100A6 Antibodies »

Product Specifications

Immunogen

Full length human S100A6 protein [Swiss-Prot# P06703] expressed in E. coli.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for S100A6 Antibody

Western Blot: S100A6 Antibody [NB110-93274]

Western Blot: S100A6 Antibody [NB110-93274]

Western Blot: S100A6 Antibody [NB110-93274] - Detection of S100A6 antibody in Hela whole cell extracts using NB110-93274.
Immunocytochemistry/ Immunofluorescence: S100A6 Antibody [NB110-93274]

Immunocytochemistry/ Immunofluorescence: S100A6 Antibody [NB110-93274]

Immunocytochemistry/Immunofluorescence: S100A6 Antibody [NB110-93274] - S100AG antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Applications for S100A6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:500

Western Blot

1:1000
Application Notes
In Western blot, where a band is seen at ~9 kDa.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole antisera

Preservative

0.1% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: S100A6

S100A6 (S100 calcium-binding protein A6) belongs to S-100 family, a family of calcium-binding proteins responsible for regulation of cytoskeletal dynamics, cell proliferation and differentiation. S100A6 protein is a 10-kD polypeptide that localize to nuclear envelope, cytoplasm and cell membranes, and exists as homodimer which interacts with CACYBP, ANXA2, ANXA11, SUGT1, TP53, tropomyosin, FKBP4, CACYBP etc. S100A6 has been suggested to function as calcium sensor and is essential to cellular calcium signaling. S100A6 can also function by interacting with other proteins and indirectly play a role in the reorganization of actin cytoskeleton as well as in cell motility. S100A6 is implicated in regulation of different cellular phenomena such as proliferation, differentiation and apoptosis, and has been associated with tumorigenesis, invasion and/or metastasis. Originally identified in murine Ehrlich ascites tumour cells, S100A6 now known to express at elevated levels in different tumours such as oral squamous cell carcinoma, colorectal adenocarcinoma, cholangiocarcinoma , neuroblastoma , as well as lung, gastric, pancreatic, breast and thyroid cancer.

Long Name

S100 Calcium Binding Protein A6

Alternate Names

CACY, MLN 4, PRA

Entrez Gene IDs

6277 (Human); 85247 (Rat)

Gene Symbol

S100A6

UniProt

P06703

Additional S100A6 Products

Product Documents for S100A6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for S100A6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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